active placebo

Definitions

  • WordNet 3.6
    • n active placebo a placebo used in experimental tests of a drug that has noticeable side effects "an active placebo mimics the side effects of the experimental drug"
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Usage


In news:

The majority of oral contraceptives (OCs) involve a regimen of 21 days of active pills followed by 7 days of placebo pills.
When it comes to the placebo effect and pain relief, the brain appears to be a much more active player than has been recognized up to now.
Improvement of Signs and Symptoms by STELARA in Patients with Active Psoriatic Arthritis: Week 52 Results of the Phase 3, Multicenter, Double-blind, Placebo-controlled PSUMMIT I Study.
Improvement of Signs and Symptoms by STELARA in Patients with Active Psoriatic Arthritis : Week 52 Results of the Phase 3, Multicenter, Double-blind, Placebo-controlled PSUMMIT I Study.
For centuries, doctors have recognised the placebo effect, in which the illusion of treatment, such as pills without an active ingredient, produces real medical benefits.
Placebo Effect's Neural Activity Photographed for First Time.
Placebo Effect's Neural Activity Photographed for First Time.
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In science:

To ensure feasibility of the simulation study, we restricted the number of occasions to m = 3 and considered a simple two-group (50 : 50 mixture) study design configuration (e.g., active treatment versus placebo), with 50 sub jects in each group.
A generalized linear mixed model for longitudinal binary data with a marginal logit link function
Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: A randomized, placebo-controlled, 52-week trial.
Detection of treatment effects by covariate-adjusted expected shortfall
H1 : θT − θP > ∆ · (θR − θP ), where θk ∈ Θ ⊆ R, k = T , R, P , is the parameter of interest, representing the efficacy of a treatment, and ∆ ∈ [0, ∞) a fixed constant expressing the amount of the active control effect relative to placebo, which should be retained.
The assessment and planning of non-inferiority trials for retention of effect hypotheses - towards a general approach
Rejecting H0 implies to claim that the test treatment achieves at least ∆ · 100% of the active control effect, at which both are compared relatively to placebo.
The assessment and planning of non-inferiority trials for retention of effect hypotheses - towards a general approach
Statistical methods for comparison to placebo in active-control trials.
The assessment and planning of non-inferiority trials for retention of effect hypotheses - towards a general approach
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