She suffered greatly from itching of the skin, due to the uremia of the kidney-disease; the skin was harsh and dry.
"Anomalies and Curiosities of Medicine" by George M. Gould
Uremia may develop at any time.
"Dietetics for Nurses" by Fairfax T. Proudfit
The natural end of patients in this group is either uremia or cardiac decompensation (so-called cardiorenal disease).
"Arteriosclerosis and Hypertension:" by Louis Marshall Warfield