• WordNet 3.6
    • n necrosis the localized death of living cells (as from infection or the interruption of blood supply)
    • ***
Webster's Revised Unabridged Dictionary
    • Necrosis (Bot) A disease of trees, in which the branches gradually dry up from the bark to the center.
    • Necrosis (Med) The pathologic death of part of a tissue due to irreversible damage. Contrast to necrobiosis, which is a normal death of cells in a tissue. Formerly, applied primarily to death of bone tissue.
    • ***
Century Dictionary and Cyclopedia
    • n necrosis In pathology, the death of a circumscribed piece of tissue. It may be produced by stoppage of the blond-supply, as in embolism, by mechanical violence, by chemical agency, or by excessive heat or cold. It may involve large masses of tissue, or small clusters of cells, or scattered individual cells. The necrosed tissue may be absorbed and replaced by normal tissue or by cicatricial tissue. It may form a caseous mass, or the cavity may fill with lymph, forming a cyst.
    • n necrosis In botany, a disease of plants, chiefly found upon the leaves and soft parenchymatous parts. It consists of small black spots, below which the substance of the plant decays. Also called spatting.
    • n necrosis A disease of the grape, attributed to Bacillus vitivorus.
    • ***
Chambers's Twentieth Century Dictionary
    • ns Necrosis the mortification of bone:
    • ns Necrosis (bot.) a disease of plants marked by small black spots
    • ***


Webster's Revised Unabridged Dictionary
NL., fr. Gr. ne`krwsis, fr. nekruy^n to make dead, to mortify, nekro`s a dead body
Chambers's Twentieth Century Dictionary
Gr. nekros, dead.


In literature:

It's what's called necrosis.
"McTeague" by Frank Norris
A peculiar feature of phosphorus-poisoning is necrosis of the jaw.
"Anomalies and Curiosities of Medicine" by George M. Gould
In other cases, however, the necrosis has spread deeper.
"Diseases of the Horse's Foot" by Harry Caulton Reeks
There was no sloughing; the swelling disappeared without any necrosis of tissue.
"Scientific American Supplement, No. 841, February 13, 1892" by Various
Where bandages of pure rubber are employed great care is necessary, if one is not experienced in their use, lest necrosis result.
"Lameness of the Horse" by John Victor Lacroix
But in the absence of the screen there is extensive necrosis of the tissues near the tubes.
"The Birth-Time of the World and Other Scientific Essays" by J. (John) Joly
It may lead to necrosis of a portion or even of the entire phalanx.
"Manual of Surgery" by Alexis Thomson and Alexander Miles
One mere boy came to me with necrosis of one side of his lower jaw due to nothing but neglected toothache.
"A Labrador Doctor" by Wilfred Thomason Grenfell
Most medical men will come to the conclusion that it was due to caries and necrosis of the bone, of syphilitic origin.
"Fasting Girls" by William Alexander Hammond
Most of her bones, in a state of necrosis, had been skilfully removed by the time the smokers had passed back.
"Somehow Good" by William de Morgan

In news:

High doses of aflatoxins result in severe hepatocellular necrosis, and prolonged low dosages result in reduced growth rate and liver enlargement.
Chief veterinarian Suzan Murray told a news conference Thursday that the cub's cause of death was liver necrosis, or the death of liver cells.
Total necrosis of the intranasal structures and soft palate as a result of nasal inhalation of crushed OxyContin.
Abstract Nasal inhalation of substances such as cocaine has long been linked to septal necrosis and more recently to palatal perforation.
Through work done at the University of Arkansas, plant pathologist Yannis Tzanetakis (pronounced Zan-tak-is) has identified a new virus which is called Soybean Vein Necrosis Virus.
High-grade B-cell lymphoma with extensive necrosis .
Serum-alkaline-phosphatase as predictor of avascular necrosis of bone in renal-transplant recipients.
The question raised by Josh Cullimore and colleagues regarding antibiotic prophylaxis with carbopenems is an important issue for the treatment of pancreatic necrosis and, as stated in our Seminar, this point is highly debated.
This effect may predispose patients to septal cartilage ischemia, necrosis and, eventually, perforation.
The pathology of vasculitis involves inflammation and necrosis of blood-vessel walls.
Disturbance of the circulation superimposed by overuse is believed to give rise to Panner's disease (capitellar osteochondrosis) in the younger athlete – an ischemic necrosis.4.
Horses at most risk of infection include those with open fractures , ischemia (lack of blood flow), necrosis (tissue death), and long bone fractures , which have a fivefold increased risk of infection, he said.
National Panda Cub Died From Liver Necrosis.
RUSHVILLE — Soybean vein necrosis virus, a new disease in Indiana soybeans , was confirmed earlier this month, a Purdue Extension plant pathologist says.
AET BioTech and BioXpress Therapeutics have entered into an agreement to codevelop a biosimilar version of Abbott's tumor necrosis factor inhibitor monoclonal antibody adalimumab.

In science:

In the center of the lesion, severe ischemia leads to rapid necrosis (Fig. 1A), but in the surrounding penumbral regions, the tissue damage evolves slowly over many hours/days (Marchal et al. 1996).
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
Mark K. S., Trickler W. J. and Miller D. W. (2001) Tumor necrosis factor-alpha induces cyclooxygenase-2 expression and prostaglandin release in brain microvessel endothelial cells. J.
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
Azab, A., Fraifeld, V., Kaplanski, J., 1998. Nimesulide prevents lipopolysaccharide-induced elevation in plasma tumor necrosis factor-alpha in rats.
Neuroprotective efficacy of nimesulide against hippocampal neuronal damage following transient forebrain ischemia
Their findings suggest that NF-κB/Rel may be a potential target for molecular therapies of leukemia. demonstrate that ectopic expression of BCR/ABL interferes with the tumor necrosis factor (TNF) signaling pathway through the down-regulation of TNF receptors.
Multiple tests of association with biological annotation metadata
Ectopic expression of protein-tyrosine kinase Bcr-Abl suppresses tumor necrosis factor (TNF)-induced NF-κB activation and IκBα phosphorylation.
Multiple tests of association with biological annotation metadata