Salicylic

Definitions

  • Webster's Revised Unabridged Dictionary
    • a Salicylic (Chem) Pertaining to, derived from, or designating, an acid formerly obtained by fusing salicin with potassium hydroxide, and now made in large quantities from phenol (carbolic acid) by the action of carbon dioxide on heated sodium phenolate. It is a white crystalline substance. It is used as an antiseptic, and in its salts in the treatment of rheumatism. Called also hydroxybenzoicacid.
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Century Dictionary and Cyclopedia
  • Interesting fact: The name Aspirin was invented from "A" in acetyl chloride. The "spir" comes from spiraea ulmaria which is the plant that they got the salicylic acid from, and the "in" was used because back then it was popular to end the name of medicines with "in."
    • salicylic Derived from the willow: applied to a number of benzene derivatives which may be derived from the glucoside salicin found in the bark and leaves of willows.
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Chambers's Twentieth Century Dictionary
  • Interesting fact: Aspirin went on sale as the first pharmaceutical drug in 1899, after Felix Hoffman, a German chemist at the drug company Bayer, successfully modified Salicylic Acid, a compound found in willow bark to produce Aspirin.
    • Salicylic obtained from the willow
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Etymology

Chambers's Twentieth Century Dictionary
L. salix, salicis, a willow.

Usage

In literature:

Her talk these days was of formaldehyde, benzoate of soda, and salicylic acid.
"Miss Billy Married" by Eleanor H. Porter
The administration of the salicylate of soda modified in degree this violaceous odor.
"Anomalies and Curiosities of Medicine" by George M. Gould
Pilocarpin, and salicylate of soda, and mercury do not tend towards cheerfulness.
"The Man" by Bram Stoker
What is sold as antifermentive is simply the well-known antiseptic, salicylate of soda.
"Science in the Kitchen." by Mrs. E. E. Kellogg
Give two drams of salicylate of soda every three hours for two days.
"Pratt's Practical Pointers on the Care of Livestock and Poultry" by Pratt Food Co.
The making of medicines from coal tar began in 1874 when Kolbe made salicylic acid from carbolic acid.
"Creative Chemistry" by Edwin E. Slosson
Jan got rather strong signs of inflammatory rheumatism threatening, so he went to bed for a couple of days with salicylate.
"The Luck of Thirteen" by Jan Gordon
Salicylates are only of service during the exacerbations attended with pyrexia.
"Manual of Surgery" by Alexis Thomson and Alexander Miles
In rheumatic cases, salicin, aspirin, and salicylate of soda are indicated.
"Manual of Surgery Volume Second: Extremities--Head--Neck. Sixth Edition." by Alexander Miles
Thus salicylic acid yields n-pimelic acid, HOOC.
"Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 1" by Various
The principal preservatives employed are salicylic and boracic acids and formalin.
"Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 3" by Various
The salicylate of colchicine is stable in water and may be given in doses of about one-thirtieth of a grain.
"Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6" by Various
To prevent book-binders glue from turning sour, add enough of the raw salicylic acid in boiling water to keep it soluble.
"Paper and Printing Recipes" by J. Sawtelle Ford
C. Fusion with alkalis converts it into salicylic acid.
"Encyclopaedia Britannica, 11th Edition, Volume 7, Slice 6" by Various
This is salicylic acid, a white crystalline compound which has been known to chemists since 1839.
"Coal" by Raphael Meldola
Yes; he would go to bed, take the morphia, and then, later, the salicylate of soda.
"Shadows of Flames" by Amelie Rives
Occasionally salicylic acid and sodium carbonate are used.
"Dietetics for Nurses" by Fairfax T. Proudfit
Beer sometimes contains salicylic acid added as a preservative.
"The New Gresham Encyclopedia. Vol. 1 Part 1" by Various
Large doses of quinine or of salicylic acid will occasion it in many patients.
"A System of Practical Medicine by American Authors, Vol. I" by Various
Salicylic acid has been widely used in this sense.
"Animal Proteins" by Hugh Garner Bennett
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In news:

They have conducted some experiments with organic anions , salicylic acid and ibuprofen.
A 22-year-old black female presented to the emergency department complaining of a bi-parietal headache for ten days relieved by salicylates.
She prescribed 26 percent salicylic acid, and the wart grew to the size of a quarter.
Salicylic acid and ammonium lactate (exfoliate).
Salicylate level This test measures the amount of salicylate (the main ingredient in aspirin and in some other NSAIDs) in the blood to determine if enough is being absorbed to effectively reduce inflammation.
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In science:

Addition of salicylate to a lipid bilayer also decreases the area per head group.
Biological and synthetic membranes: What can be learned from a coarse-grained description?
Evans blue (2% in saline, 4 mL/kg) was injected to rats via the tail vein under diethyl ether anesthesia at different times (time course experiment) or at 46 h after the onset of MCAO (for evaluating the effect of nimesulide and valeryl salicylate; see below Section ‘Treatment groups and drug administration’).
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
The COX-1 selective inhibitor valeryl salicylate (VAS) failed to confer any protective effect, when administered immediately after ischemia, or in a delayed fashion.
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
Production of PGE2 in the ischemic cerebral cortex is potently reduced by the COX-2 inhibitor nimesulide, but only very modestly diminished by the highest dose of the COX-1 inhibitor valeryl salicylate (VAS).
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
In all cases, transducers were bonded to samples using phenyl salicylate and silicone for room and low temperature measurements respectively.
Elastic Tensor of YNi_2B_2C
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