Chloral

Definitions

  • Webster's Revised Unabridged Dictionary
    • Chloral (Chem) A colorless oily liquid, CCl3.CHO, of a pungent odor and harsh taste, obtained by the action of chlorine upon ordinary or ethyl alcohol.
    • Chloral (Med) Chloral hydrate.
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Century Dictionary and Cyclopedia
    • n chloral A colorless mobile liquid (CCl3.CHO), having an agreeable pungent smell and biting taste, first prepared by Liebig from chlorin and alcohol, afterward by Städeler by the action of chlorin on starch. The hydrate of chloral (CCl3. CH(OH)2), as now prepared, is a white crystalline substance having a pungent odor and an acrid taste. In contact with alkalis it separates into chloroform and formic acid. In medicine it is used as a hypnotic, and in doses of from 15 to 30 grains usually produces calm sleep, which lasts for several hours, and is not followed by unpleasant effects, such as frequently attend the use of morphine. In overdoses it paralyzes the nerve-centers, arresting respiration and the action of the heart, and causes death.” When used continuously it may produce very serious effects on the system.
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Chambers's Twentieth Century Dictionary
    • ns Chloral a limpid, colourless, oily liquid, with a peculiar penetrating odour, formed when anhydrous alcohol is acted on by dry chlorine gas
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Etymology

Webster's Revised Unabridged Dictionary
Chlor,ine + al,cohol
Chambers's Twentieth Century Dictionary
Gr. chlōros, pale-green.

Usage

In literature:

It is then cleared in alkali, or in chloral hydrate.
"All About Coffee" by William H. Ukers
But when the chloral was stoutly met at last, it was too late.
"Great Men and Famous Women, Vol. 8 (of 8)" by Various
To dilate the blood vessels give chloral hydrate.
"Special Report on Diseases of Cattle" by U.S. Department of Agriculture
People did not die now-a-days, either of broken hearts or of chloral, when their lovers deserted them.
"Brooke's Daughter" by Adeline Sergeant
He rose, went to the bath-room and took a bottle of chloral from the medicine-closet.
"The Destroying Angel" by Louis Joseph Vance
A dose of chloral in their wine had attended to the certainty of their slumbers.
"Tiger Cat" by David H. Keller
The thing I had unmistakably tasted was chloral hydrate.
"The Man Who Couldn't Sleep" by Arthur Stringer
Tenantless; and the cup of tea, heavily drugged with a solution of chloral, stood where it had been placed, untouched, upon the table.
"The Man with a Shadow" by George Manville Fenn
One was endorsed "Sleeping-draught," the other "Poison," and "Chloral.
"A Mysterious Disappearance" by Gordon Holmes
I don't want to become a chloral fiend.
"Phases of an Inferior Planet" by Ellen Glasgow
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In poetry:

Far footfalls clank.
The bad burn waits with his head unbandaged.
My neighbour chokes in the clutch of chloral . . .
O, a gruesome world!
"Interior" by William Ernest Henley

In science:

Surgical preparation and procedure for inducing transient focal cerebral ischemia Rats were anesthetized with chloral hydrate (300 mg/kg body weight, i.p.).
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
Two hours after the EB injection, the rats were anesthetized with chloral hydrate and perfused with physiological saline through the left ventricle until colorless perfusion fluid was obtained from the vena cava (150-200 mL of saline).
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
These animals were housed five per cage, exposed to a 12-h light/dark cycle, and had free access to food and water throughout the study period. The gerbils were anesthetized with chloral hydrate (300 mg/kg, i.p.).
Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils
Male Mongolian gerbils (Meriones unguiculatus; 60-75 g) were anesthetized with chloral hydrate (300 mg/kg, i.p.) and subjected to both common carotid arteries occlusion for 5 min, exactly as in our previous work .
The highly selective cyclooxygenase-2 inhibitor DFU is neuroprotective when given several hours after transient cerebral ischemia in gerbils
Permanent focal ischemia model Rats were anesthetized with chloral hydrate (300 mg/kg body weight, i.p.). Once surgical levels of anesthesia were attained (assessed by absence of hind leg withdrawal to pinch), ischemia was induced by using an occluding intraluminal suture [9,22,24].
Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats
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